symex GmbH & Co. KG
About us
symex is a leading international manufacturer of mixing and homogenizing systems for the pharmaceutical, cosmetics, and chemical industries, with more than 1,000 reference plants worldwide. We develop solutions for the production of liquids, semi-solids, and solids—from laboratory scale (4 liters) to fully automated turnkey process systems for large-scale industrial production (20,000 liters). Our mixing systems stand for maximum process stability, reproducible product quality, and efficiency increases of up to 85%.
We have been supporting our customers as a partner since 1997 – from the initial idea to global service.
Address
Lengstr. 10
27572 Bremerhaven
Germany
E-mail: info@symex.de
Phone: +49 471 984010
Internet: www.symex-mixing.com
Contact person:
Ulf Sieckmann
CEO/ Managing Director
E-mail: sales@symex.de
Phone: +49 471 984010
Products & Services
Turn-Key Projects
Custom and Standard Mixing and Homogenizing Systems for liquids, semi-solids and solids
Mixer/ homogenizer (30 to 20,000 liters)
Laboratory mixer (4 liters)
Pilot mixer (30 liters)
In-Line homogenizer (Mixer)
Digitalization package (Industry 5.0)
Software solutions for mixer/ homogenizer
Service for mixer/ homogenizer
symex Product Advantages
PAYBACK: Return-on-Invest between 6 to 12 months, due to shortest process times and highest product quality.
ALLROUNDER: Universal mixing system for all product forms.
FLEXIBILITY: Batch sizes of 10%-100% with identical product characteristics.
PRODUCTIVITY: Process and cleaning times reduced by up to 75%.
INNOVATIONS: Industry 5.0 - Digitalization concept with a patented App-Solution.
SUCCESS: Right First Time (RFT): No flawed batches or reworking due to 100% reproducible processes.
QUALITY: Better products – consistent homogeneity, particle size, viscosity and stability.
Industries and Applications:
Cosmetics/ Personal Care:
Creams, Serums, Lotions, Foundation, Make-up, Lipstick, Mascara, Eyeliner, Shampoo, Sunscreen, Rouge, Bronzer etc.
Pharma/ Healthcare:
Cough syrup, Eye/ Ear Drops, Nasal Spray, Suppository,, Ointments, Creams, Toothpaste, Gel, Capsules.
Chemistry:
Lubricants, Colors, Grease, Fertilizer, Varnishes, Adhesives, Car Polish.
First-class Service: 24/7 worldwide:
Maintenance
Trainings
Engineering
Qualification GMP and FDA compliant
Scale up
symex mixer/ homogenizer (30 to 20,000 liters)
The symex all-round mixing system for maximum batch size flexibility from 10 to 100% batch size.
For the production of liquid to semi-solid products - with low to high viscosity. Emulsions, ointments, gels, creams, sunscreen, makeup, foundation, mascara, eyeliner, lipstick, toothpaste, lubricants, and fertilizers.
Technical equipment – adaptable to application/location/premises
Coaxial agitator with central and scraper agitator
Original Co-Twister rotor-rotor homogenizer (independent control of flow and shear)
Fully automatic system control
App platform (remote access to system data, process conditions, and reports)
Validated complete cleaning between 20 and 45 minutes (CIP)
External + internal circulation line (first-in-first-out principle)
Hot/cold emulsification process directly in the shear gap
Direct suction of liquids, powders, granulates, pellets
Temperature control system (accurate to +/- 0.5°C)
Raw material dosing system
Pressure/vacuum vessel with double jacket according to ASME, PED, JIS, CRN, Gost, China Stamp
Optional: Lid lift with lifting column - Phase container with transfer system, operating platform.
Digitalization package (Industry 5.0)
Fully automated batch execution (in-line process and quality control with “golden batch” verification)
Real-time digital process simulation (virtual twin)
Sustainability assurance (comprehensive energy monitoring, analysis, and documentation, including calculation of carbon footprint)
Predictive maintenance (condition analysis, full transparency, and planning reliability for maintenance, service intervals, and spare parts throughout the entire life cycle)
symex pre-phase mixer
Increase efficiency. Reduce costs.
symex pre-phase vessels are available in all sizes for water and fat phases and increase productivity while reducing operating costs.
Fats and oils, pellets, and wax blocks are melted in no time and brought to process temperature. Crushing, grinding, and mixing are carried out in a single, closed process step – efficiently, reproducibly, and with minimal material loss.
Automated transfer to the main mixer ensures that recipes are executed precisely and uniformly. Each batch is fully documented in accordance with 21 CFR Part 11 and archived in an audit-proof manner. The integrated hot-cold process control with direct introduction into the homogenizer shear gap shortens process times by up to 75% while increasing process stability.
The symex control system also automatically recognizes mobile pre-phase containers and prevents misassignments or individual recipe executions – for maximum process reliability and reproducible quality.
symex laboratory mixer (4 liters)
100% scalable symex laboratory system for test and trial series in product development:
Precise measurement data from small batches of 1 to 4 liters
Transferable to real production plants
Technical design corresponds in every detail to a large plant.
Realistic representation of the production of emulsions, suspensions, creams, gels, and surfactant products for cosmetic, pharmaceutical, and chemical product development.
Technical features:
Compact design on a mobile laboratory table
Anchor stirrer with two current breakers and temperature sensor
Rotor-stator homogenizer: infinitely variable speed control with external circulation line (long circulation & short circulation)
Touch display including user management and process data recording
Suction system for powders and liquids on the homogenizer
Integrated CIP system
Compact electric temperature control unit for heating and cooling the double jacket in the secondary circuit.
Pressure/vacuum resistance
symex service for mixer/ homogenizer
24/7 symex service & after sales
Since 1997, fast, competent service in mixing and homogenization technology.
Worldwide on-site service
Customized maintenance & preventive service
Extensions, upgrades, and modernization of existing plant systems
Remote service
Comprehensive on-site training in theory and practice
Fast fault analysis & repair
Expertise for all mixing systems – including third-party brands
Service hotline: +49 471 98 40 1 0
symex software solutions for mixer/ homogenizer
The proprietary “symex Industry 5.0 digitization concept” sets new standards in the process industry. It enables consistently networked, flexible, and highly automated production of pharmaceutical, cosmetic, and chemical products—including ointments, gels, makeup, mascara, lubricants, fertilizers, and much more.
Five technically coordinated modules raise the bar for process reliability, efficiency, sustainability, and maximum flexibility to a whole new level. Resistant to external circumstances.
The modular architecture allows for flexible combination of functional modules. These include:
App platform (remote access to plant data, process conditions, and reports)
Fully automated recipe execution and management (in-line process and quality control with “golden batch” verification)
Real-time digital process simulation (virtual twin)
Sustainability assurance (comprehensive energy monitoring, analysis, and documentation, including CO2 footprint calculation)
Predictive maintenance (condition analysis, full transparency, and planning reliability for maintenance, service intervals, and spare parts throughout the entire life cycle)
All modules can also be retrofitted to existing production systems.
The concept was officially awarded the LOSGRÖSSE 1+ Award in 2025.
symex pilot mixer (30 liters)
symex pilot mixers are used in product and process development (scale-up) of smaller product batches/product samples up to 30 liters and provide accurate measurement data in small batches that can be transferred to real production mixer.
Semi-solid and liquid products, such as oil-in-water and water-in-oil emulsions, fine and coarse suspensions, and viscosities up to 2,000,000 cP can be produced.
Technical features
Compact design, identical in construction to the process mixer
Ready for immediate use/can be used independently of location
Coaxial agitator with central and scraper agitator
Original Co-Twister rotor-rotor homogenizer (independent control of flow and shear)
Fully automatic system control
App platform (remote access to system data, process conditions, and reports)
Validated complete cleaning between 20 and 45 minutes (CIP)
External + internal circulation line (first-in-first-out principle)
Hot/cold emulsification process directly in the shear gap
Direct suction of liquids, powders, granulates, pellets
Temperature control system (accurate to +/- 0.5°C)
Raw material dosing system
Pressure/vacuum vessel with double jacket according to ASME, PED, JIS, CRN, Gost, China Stamp
symex In-Line homogenizer (Mixer)
The symex In-Line Homogenizer temporarily or permanently expands production facilities, thereby increasing product availability for demanding applications. Thanks to the flexible accessory concept, systems can be upgraded as needed—without extensive modifications.
Available on a mobile transport trolley or as a stationary solution in a frame, the system can be optimally integrated into existing production environments. The homogenizer ensures uniform particle distribution and a defined, reproducible texture when processing liquids and suspensions. Different sizes and connection variants enable use in the cosmetics, pharmaceutical, and chemical industries—even with complex formulations and high quality requirements.
Technical equipment
Homogenizer type 1: Rotor-stator principle
Homogenizer type 2: Rotor-rotor principle (original Co-Twister)
Air- or water-cooled, speed-controlled drive
Double-acting mechanical seal, cooled and lubricated by monitored barrier fluid system (standard or aseptic)
Touch panel and connection option to existing control systems
Stainless steel housing, soundproofed lining